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KMID : 0359719940120010030
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Journal of the Korean Neurological Association
1994 Volume.12 No. 1 p.30 ~ p.40
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Clinical, EEG and MRI Findings in Newly Referrd Seizure patients
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Abstract
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Clinical, EEG and MRI assessments were conducted in 320 consecutive seizure patients referred to the Yonsei Epilepsy Clinic from october 1, 1991 to Feburary 28, 1993. Clinical assessment suggested that 91.9% of had partial seizures and only 8.1%
had
generalized seizures. Among partial seizures, temporal lobe seizure was considered in 37.5%, localization undetermined partial seizure I 29.7%, extratemporal lobe seizure in 24.7%. Correlation with EEG findings in these patients showed
disconcordance
rate of 34.6% in generalized seizure, 29.1% in extratemporal lobe seizure, 15.8% in temporal lobe seizure, 5.3% in localization undetermined partial seizure. Structural lesions in MRI were found in 51.6% with hippocampal atrophy being the most
frequently found(59.4%). Focal encephalomalacia comprised 15.8%, focal atrophy in 4.8%, vascular malformation in 4.2%, granuloma in 3.7%, tumor in 3.7%, cyst in 2.4%. Patients with clinically judged temporal lobe seizure had the most common
structural
lesions in MRI, which were seen in 59.2%. Extratemporal lobe seizure had focal lesion in 50.6%, localization undetermined partial seizure in 50.5%, and generalized seizure in 23.1%. Among 98 patients with hippocampal atrophy, 27 patients(27.6%)
had
dual
pathology with focal encephalomalacia being the most common. 11 patients(11.3%) were suspected to have bilateral hippocampal atrophy. Hippocampal atrophy was more commonly seen in patients with history of febrile convulsion and in patients with
severe
seizure.
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KEYWORD
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